Gene
stx11b.2
- ID
- ZDB-GENE-050417-148
- Name
- syntaxin 11b, tandem duplicate 2
- Symbol
- stx11b.2 Nomenclature History
- Previous Names
-
- zgc:112055
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport; synaptic vesicle fusion to presynaptic active zone membrane; and vesicle docking. Predicted to localize to several cellular components, including SNARE complex; presynaptic active zone membrane; and synaptic vesicle. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 4. Orthologous to human STX11 (syntaxin 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112055 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial hemophagocytic lymphohistiocytosis 4 | Alliance | Hemophagocytic lymphohistiocytosis, familial, 4 | 603552 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | SNARE | Syntaxin | Syntaxin, N-terminal domain | Target SNARE coiled-coil homology domain |
|---|---|---|---|---|---|
|
UniProtKB:A8E5D3
|
288 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stx11b.2-201
(1)
|
Ensembl | 1,368 nt | ||
| mRNA |
stx11b.2-202
(1)
|
Ensembl | 882 nt |
Interactions and Pathways
No data available
Plasmids
No data available